Biomarker bioanalysis

The bioanalysis of endogenous biomarkers requires a broad range of expertise. Biomarker molecules vary extensively with respect to concentrations that need to be quantified, the biomarker class and its’ chemical characteristics, as well as the levels of the biomarker already present in the sample matrix.

In the case of biomarker analysis the context-of-use of the analytical data is key in developing a method that is fit for the purpose. A different challenging aspects could be that the biomarker analyte is not available as a reference material.